Corticostriatal circuits encode behavioral transitions in natural behavior

Joel Sjöbom, Lund University


In natural behavior, we fluidly change from one type of activity to another in a sequence of motor patterns. Cortical and striatal circuits are thought to have a particularly important role in the construction of action sequences, but neuronal coding of a sequential behavior consisting of different motor programs has not been investigated at the circuit-level, making the exact nature of this involvement elusive. Here I will talk about how activity in motor cortex and dorsal striatum are related to action sequencing in a complex spontaneous behavior - rodent self-grooming.